The relationship between theory and place has remained a central problem for the discipline of anthropology. Focusing on debates around the concepts of human rights and networks, specifically as these traverse African and Melanesian contexts, this article highlights how novel ideas emerge through sustained comparison across different regions. Rather than understanding places as sources of theories to be applied to other contexts, we argue that anthropologists need to recognize how new concepts are generated through reflexive comparison across different regions. This analysis leads us to question a widespread propensity to understand places as the sine qua non of anthropological theory, proposing instead that place emerges retrospectively as an artifact of comparison. We conclude that while it is therefore necessary to acknowledge the analytic construction of Africa and its sub-regions, there remain compelling reasons to recognize its analytic utility.