This essay answers the question: what is interpretation? It does so by proposing that interpretation involves certain brain operations. These utilize perceptual and procedural culture stored in neural networks. The parts of the brain performing interpretation are said to constitute a cultural neurohermenetic system, hypothesized to function according to an interpretive hierarchy. It is argued that such an approach has two benefits. The first of these is to provide a non-sociobiological, non-reductionist way of analyzing interactions between culture and biology. The second benefit is to provide conceptual tools for explaining how the micro-realm within individuals (I-space) makes connections in the macro-realm (E-space) of events in social forms. Conceptualization of such connections forms a basis for a variety of social analysis termed complex string being theory.